Synera is a brand name of lidocaine/tetracaine topical, approved by the FDA in the following formulation(s):
SYNERA (lidocaine; tetracaine - patch; topical)
Manufacturer: ZARS PHARM
Approval date: June 23, 2005
Strength(s): 70MG;70MG [RLD]
Has a generic version of Synera been approved?
No. There is currently no therapeutically equivalent version of Synera available.
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Synera. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: About generic drugs.
Related Patents
Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.
Apparatus and methods for improved noninvasive dermal administration of pharmaceuticals
Patent 5,658,583
Issued: August 19, 1997
Inventor(s): Zhang; Jie & Zhang; Hao
An apparatus, product formulation, and method for improved dermal permeation of pharmaceuticals wherein the apparatus includes a thin drug formulation reservoir and a heat-generating chamber separated by a first non-permeable wall, wherein the reservoir and chamber are formed in or supported by a housing. The drug formulation reservoir houses or is capable of housing a predetermined amount of a formulation containing pharmaceutically-active agent(s). The heat-generating/temperature-regulating chamber includes a medium for generating controlled heat, preferably a chemical composition made of carbon, iron, water and/or salt which is activated upon contact with air (oxygen). The function of the heat-generating/temperature-regulating element is to heat the user's skin, rapidly bring the skin temperature to a desired and elevated narrow range and keep it in this range for sufficient time to obtain more rapid, enhanced and less variable dermal absorption of selected pharmaceutically-active agents and to obtain improved clinical effects. Structure for controlling the generation of heat is also disclosed. The apparatus may optionally include a spacing or standoff structure which spans the drug formulation reservoir between the non-permeable wall and the user's skin surface for maintaining a predetermined thickness of the drug formulation on the user's skin surface. Also, a novel product formulation which can be used with the apparatus which uses high percentage of eutectic mixture of local anesthetics to reduce the overall degradation rate of the local anesthetic compound(s) in formulations which are subject to hydrolysis.
Patent expiration dates:
- July 28, 2015
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Drug product
Noninvasive dermal anesthetics
Patent 5,919,479
Issued: July 6, 1999
Inventor(s): Zhang; Jie & Zhang; Hao
Assignee(s): Zars, Inc.
An apparatus, product formulation, and method for improved dermal permeation of pharmaceuticals wherein the apparatus includes a thin drug formulation reservoir and a heat-generating chamber separated by a first non-permeable wall, wherein the reservoir and chamber are formed in or supported by a housing. The drug formulation reservoir houses or is capable of housing a predetermined amount of a formulation containing pharmaceutically-active agent(s). The heat-generating/temperature-regulating chamber includes a medium for generating controlled heat, preferably a chemical composition made of carbon, iron, water and/or salt which is activated upon contact with air (oxygen). The function of the heat-generating/temperature-regulating element is to heat the user's skin, rapidly bring the skin temperature to a desired and elevated narrow range and keep it in this range for sufficient time to obtain more rapid, enhanced and less variable dermal absorption of selected pharmaceutically-active agents and to obtain improved clinical effects. Structure for controlling the generation of heat is also disclosed. The apparatus may optionally include a spacing or standoff structure which spans the drug formulation reservoir between the non-permeable wall and the user's skin surface for maintaining a predetermined thickness of the drug formulation on the user's skin surface. Also, a novel product formulation which can be used with the apparatus which uses high percentage of eutectic mixture of local anesthetics to reduce the overall degradation rate of the local anesthetic compound(s) in formulations which are subject to hydrolysis.
Patent expiration dates:
- July 28, 2015
✓
Drug product
Apparatus for heating to a desired temperature for improved administration of pharmaceutically active compounds
Patent 6,306,431
Issued: October 23, 2001
Inventor(s): Zhang; Jie & Zhang; Hao
Assignee(s): Zars, Inc.
Methods and apparatus for improving administration of drugs through the use of heat and other physical means. The present invention relates to the use of heat and other physical means in conjunction with specially designed dermal drug delivery systems, conventional commercial dermal drug delivery systems, or drugs delivered into a sub-skin depot site via injection and other methods to alter, mainly increase, the drug release rate from the dermal drug delivery systems or the depot sites to accommodate certain clinical needs.
Patent expiration dates:
- July 28, 2015
✓
Drug product
Method for facilitating absorption of pharmaceutically active compounds
Patent 6,465,006
Issued: October 15, 2002
Inventor(s): Jie; Zhang & Hao; Zhang
Assignee(s): Zars, Inc.
Methods and apparatus for improving administration of drugs through the use of heat and other physical means. The present invention relates to the use of heat and other physical means in conjunction with specially designed dermal drug delivery systems, conventional commercial dermal drug delivery systems, or drugs delivered into a sub-skin depot site via injection and other methods to alter, mainly increase, the drug release rate from the dermal drug delivery systems or the depot sites to accommodate certain clinical needs.
Patent expiration dates:
- July 28, 2015
✓
Drug product
Integrated apparatus for controlled heat aided dermal drug delivery
Patent 6,546,281
Issued: April 8, 2003
Inventor(s): Jie; Zhang & Hao; Zhang & Wade A.; Hull & Larry; Rigby
Assignee(s): Zars, Inc.
An integrated apparatus for controlled heat aided dermal drug delivery is disclosed. The apparatus has a temperature control component and a drug delivery component. The temperature control component may and dermal drug delivery component are an integrated unit. The apparatus also comprises means to prevent exchange of substance(s) among the heat generating component, the drug delivery component and the outside environment. The apparatus is designed to be easy to use.
Patent expiration dates:
- July 28, 2015
✓
Drug product
Method and apparatus for improved heat controlled administration of pharmaceuticals
Patent 6,780,426
Issued: August 24, 2004
Inventor(s): Jie; Zhang & Hao; Zhang
Assignee(s): Zars, Inc.
The present invention features methods and apparatus'for improving administration of drugs through the use of specifically controlled heat and other physical means. The present invention relates to the use of heat and other physical means in conjunction with specially designed dermal drug delivery systems, conventional commercial dermal drug delivery systems, or drugs delivered into a sub-skin depot site via injection and other methods to alter, mainly increase, the drug release rate from the dermal drug delivery systems or the depot sites to accommodate certain clinical needs.
Patent expiration dates:
- July 28, 2015
✓
Drug product
See also...
- Synera Consumer Information (Drugs.com)
- Synera Patch Consumer Information (Wolters Kluwer)
- Synera Advanced Consumer Information (Micromedex)
- Lidocaine/Tetracaine Patch Consumer Information (Wolters Kluwer)
- Lidocaine and tetracaine Topical application Advanced Consumer Information (Micromedex)
